This is a recently developed an inverted biological microscope. It is mainly designed for cell culture observation. It has great improvement in the optical resolution. It uses a long life-time LED light source for both brightfield/Phase contrast (BF/Ph)and fluorescence imaging. It has a compact and stable main body. The operation buttons are well designed. The cells, bacteria or virus can be easily observed, sampled, manipulated or injected while using on the bench or inside a hood. A viewing head and Phase Contrast illumination can be detached, which also allows using the system inside an incubator. It includes 3 different color filters, with large selection for different dyes. High power and much uniform LED illumination provides high quality fluorescence observation. With a special design of video camera port, BioXcope camera and image acquisition software, you can expect low noise, high sensitive and great resolution images from this microscope.
It scans a region of interest (ROI) or well-plate quickly. For instance scanning 96 wells using 20x obj lens with autofocus on center of each well takes just 2.5 minutes.
Inverted biological microscope, with BF,Ph and FL imaging capability, 4x, 10x, 20x, 40x obj lenses, 3 LED FL channels, motorized XY stage with various slide holders, side video camera port, intelligent light intensity control makes it an excellent choice for the labs look for a high quality live cell imaging microscopy system for cell cultures, bacteria, video time-lapse imaging, microfluidics and MEMS, virus study. vaccine development.
Advanced Microscope for Live Cell Imaging
Ergonomic Design, Comfortable Operation
45° Inclined Viewing Head
Inclined viewing head helps the microscope user to operate it in a very comfortable position. Minimizes muscle tension and discomfort that may happen during long working hours.
Long-handle Mechanical Stage
The user can comfortably and smoothly move the sample during the operation.
Fits inside an incubator
You might need to remove the viewing head depending on the incubator internal size. You will get a cap to block the port.
Depth with viewing head is 559mm; it becomes 470mm after removal.
Memorized Objective Lenses
The system can remember the suitable light intensity for each objective lens. Illumination brightness needs to be adjusted once. The microscope will take care of the rest. This helps visual fatigue and improves the work efficiency.
Intelligent Light Intensity Control
The liquid crystal screen at top shows and remembers the selected objective lens and its proper brightness. The system can show the different working modes of start, lock, turn off, hybernate / standby modes.
Easy Operation in Sterile Condition
The microscope’s size is kept at relatively small and compact size, and its weight as low as possible. The microscope body has anti-UV coating. It can be cleaned and sterilized under UV lamp.
Various Sample Holders
Various design of sample holders are available for different cell culture containers, microfluidics chambers and MEMS devices. This includes glass slide holder (single and double size), 35mm Petridish, 54mm Petri Dish, 65mm Petri-dish, 90mm PD, Terasaki Holder, T-25 flask, T-75 flask, universal holder and of course custom sample holder.
Phase Contrast Imaging
By reference index changes, high contrast microscopy images of transparent samples such as cell culture become available. This requires no staining or using a dye.
Hoffman Modulation Phase Contrast
With slant light, changing phase gradient into light intensity variety, it can be used to observe unstained cells and living cells.
3D Emboss Contrast
Without any extra optical component, no glare 3D image can be obtained just through adding adjustment slider for both glass & plastic Petridishes.
LED Fluorescence
Uniform brightness, easy to use and long life-time LED, replaces the old HBO, saves time and money while brings quality.
3 Fluorescence Filter blocks are available
UV, Blue and Green excitation, combined with blue, green and red emission filters are very common choices for most of the labs. Dapi/Hoechst, GFP/FITC, TRITC/Texas Red/ mCherry/ tdTomato are very popular among the list of fluorophores that we customize the filters and LEDs for. We also offer IR and NIR filters, and relevant optics.
Contrast Shield
The Contrast Shield, specifically designed for this microscope, can effectively block the interference of the external light, increases the contrast of the fluorescent image, and provides a high signal-to-noise ratio fluorescent image. When the phase contrast observation is required, the Contrast Shield can be removed conveniently from the light path in matter of seconds.
Automation
Motorized XY stage
Autofocus
Autoexposure, autogain, manual exposure and gain
Control the microscope using a smartphone app
White balance, dark balance, natural color image
Super fast scanning and focusing (20mm/sec)
Travel Range: 125mm (X) x 75mm (Y), a microwellplate size
Precision at ±0.1um in XY and Z.
Fast Scan on ROI or a well plate,
Super Fast Scan; For instance scanning 96 wells using 20x obj lens with autofocus on center of each well takes just 2.5 minutes.
Scanning Modes: line by line, zig-zag, line autofocus, polyline autofocus scan,…
Automation
Model
BioXcope I600A
Moving Range
X:125mm,Y:75mm
Min step size
0.1um
Repeated positioning accuracy
±1.5um
Max speed
20mm/s
Scanning
Super Fast Scan; For instance scanning 96 wells using 20x obj lens with autofocus on center of each well takes just 2.5 minutes.
Scanning Modes: line by line, zig-zag, line autofocus, polyline autofocus scan,…
Size
275*239*44.5 (mm)
Limitation
+ software limitation
+ mechanical position limitation
+ Photoelectric switch limitation
Z Repeated positioning accuracy
Average:±1.5um,Near the focus:±0.1um
Z Max speed
10 r/s
Rocker
3D controllable rocker,Four speed
Port
USB2.0 and RS232
BAUD
9600
Specifications
Model
BioXcope I
610
620
Optical System
NIS Infinite Optical System (F200)
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Observation Method
· Brightfield
· Phase Contrast
· Hoffman Phase Contrast
· Emboss Contrast
· Epi Fluorescence
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Illumination
Transmitted Illumination
3W S-LED
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3W S-LED Kohler Illumination
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Episcopic Illumination
· LED Illuminator,
· Built-in Fly- eye Lens,
· Configure up to 3 channels,
· LED Units;
· Available Wavelengths: 365, 405, 485, 525nm
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Viewing Head
Seidentopf Viewing Head, Inclined at 45°, Interpupillary 48-75mm; Additional Camera Port, Eyepiece /Port 100/0 ∶ 0/100
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Eyepiece
Magnification (FOV)
· SW10x (22)
· WF15x (16)
· WF20x (12)
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Focusing
Coaxial Coarse and Fine Adjustment, the Function of Coarse Tightness Adjustment, Fine Division 1 um, Fine Stroke 0.2mm per Rotation, Coarse Stroke 37.5mm per Rotation. Up 7mm, Down 1.5mm.
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Nosepiece
Quintuple Nosepiece
Coded Quintuple Nosepiece
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LCD Screen
Function Display Magnification, Sleep time, Bright- ness Indication, Lock mode, etc.
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Condenser
Condenser NA 0.3, WD 75mm, without Condenser WD 187mm
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Stage
Stage: 170(X)× 250(Y)mm
Attachable Mechanical Stage: 128(X)× 80(Y), Accepts 5 Types of Microtest plate, well Clamper and Stage Clip.
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Holder
· Petri Dish Holder 35mm,
· Petri Dish Holder 90mm,
· Terasaki Holder for Terasaki Plate and ø65 dish,
· Slide Glass Holder for Glass Slides and ø54 Dish,
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