IncuScope IS500 Brightfield / Fluorescence Inverted Incubator Microscopes

  • Inverted Biological Microscope
  • Brightfield and fluorescnce imaging
  • GFP Fluorescnce as default (EX 482/35, EM 536/40nm, DM 506) or select any fluorescence filter from UV to Infrared
  • 1.4 to 16 MP Camera
  • 1.25x-100x objective lenses.
  • Incubator Microscope; fits inside hood or incubator
  • LED illumination
  • Built-in camera
  • Great Time-Lapse Imaging Software with turn on/off lights (digital shutter)

$USD 4,249.00

IncuScope IS500 Incubator Microscope:  Small, Smart & Simple

What is an IncuScope?
The IncuScope is a low price, small, compact, USB-based, portable digital inverted brightfield and epi-fluorescence microscope. The microscope fits on a shelf inside an incubator or inside a hood. It has a built-in digital camera and light source. This runs on a laptop or desktop using just one USB cable and captures fluorescence and/or brightfield images. Available with a variety of objective lenses from 1.25x to 100x. The software allows doing time-lapse study and controlling the light to turn on/off to avoid photo-bleaching and photo-toxicity. Thus, this saves paying for heating stage or miniature incubator, mechanical shutter, digital camera and fluorescence attachment which are important components for live cell imaging application. Its price is the lowest in the live cell imaging field. A side-by-side comparison with similar products such as Lumascope, Juli, EVOS, this has better images. When it comes to the price, this is the most economic choice. Last but not least, you can check your cell culture inside an incubator via Internet or smart-phone if you connect the IncuScope computer to Internet / WiFi and use our remote-control software.

Contact Us for Free Demo, a Quote , and Custom Design with 6 colors or OEM.

Why IncuScope?

There is no greatness where there is not simplicity Leo Tolstoy, quoted in The week.

  • Simple: the most simple digital microscope in the world, requires no setup, almost no training, instant installation, familiar PC environment.
  • Affordable: The lowest price video time-lapse microscope in the world.
  • Your cells are always happy since they never leave incubator.
  • Using our remote-control software/app you can see inside your incubator via Internet or iPhone, Android, Blackberry

Highlighted Applications:

  • Long-term live cell imaging in single and time lapse modes
  • Cell doubling and movement measurements
  • Stem cell differentiation movies
  • More sophisticated uses are also easily achieved with the IncuScope: cell counting or hemocytometry and growth monitoring. Using the IncuScope, it is possible to monitor cells remotely through the web from within a tissue culture incubator, overnight, away from the lab.

Unlimited Scientific and Routine Applications 

  • Microfluidics field, lab-on-chip, MEMS
  • Viral infections, HIV/AIDS study and all level III safety labs
  • Embryology, In Vitro Fertilization (IVF) studies
  • Bacteriology
  • Stem Cell Colony formation  study (long term live cell imaging)
  • Transfections, knock-out studies such as siRNA tagged
  • Drug discovery research and clinical labs
  • Field microscopy, such as marine biology
  • Proliferation assay
  • Kinetic cell migration assay
  • Kinetic angiogenesis
  • Cell invasion
  • Cytotoxicity
  • Cell culture quality control
  • Apoptosis

Colorful brigtfield images (available with iS500BF model only)

  • Yields a magnification on familiar laptop displays of approximately 20× with a field of view of 1 mm square.
  • Standard filter sets
  • Brightfield capability included. Phase Contrast is optional.
  • Time-lapse study with turn on/off light (without using a shutter!)
  • USB 3.0 interface, enabling easy integration with larger systems and remote monitoring
  • Small enough to fit on a desk, lab bench, in an incubator or tissue culture hood (approximately 190 x 125 x 115 mm or 7.5 x 5 x 4.5 in).
  • #1 Performance/Price in the Market; it saves paying to heating stage, shutter and camera, e.g. compare it with Zeiss

Price: The best price in the imaging market:

  • LumaScope LS500 ( > $8,000)
  • Juli (> $15,000)
  • EVOS (> $27,000)
  • IncuCyte (> $77,000)

Compact & Turn-Key Imaging Solutions:IncuScope

What is IncuScope?
IncuScope is a compact inverted fluorescence microscope that fits on a shelf inside an incubator or inside a hood. It has a built-in camera and LED light source. This system runs on a laptop/desktop using just one USB cable, allows capturing fluorescence and bright field images, and has several options of objective lenses and fluorescent filters. The IncuScope is the most simple and affordable live cell imaging device in the market.


  • Fits inside a hood or an incubator (saves heating stage, operates in natural environment of incubator and sterile condition)
  • USB-based camera & LED illumination
  • Avoids photo-toxicity & photo-bleaching (digital shutter)
  • The best performance/price live cell imaging device in the market
  • Extremely simple and user-friendly software & hardware
  • Remote control (browser based, iPhone or Android Apps to see inside an incubator!)
OpticsInfinity-corrected objective with an RMS thread type
Image Resolution1920×1200 pixels  =  2.3 MP; 1/1.9″(7.20×4.5)

CMOS Sensor (3.75×3.75 microns/pixels)

Image FormatsJPEG, TIF, BMP, GIF, PNG.
OpticsChroma or Omega Optical Filters
Image Size100 kB-4MB
Objectives1.25x, 2x, 4x, 5x, 10x, 20x, 40x, 50x (oil), 60x (dry), 100x (water, or air/oil) (optional)


Excitation: 482/35 BrightLine Bandpass
Emission: 536/40 BrightLine Bandpass
Dichroic Mirror: 506 nm BrightLine Dichroic Beam Splitter
FluorophoresGFP (EGFP), FITC (Fluorescein), Alexa Fluor488, SuperGlo GFP, wild type GFP (non-UV excitation), red-shifted GFP (S65T), BODIPY, Cy2, Calcein, MitoTracker Green, Oregon Green.
PC communicationUSB 3.0 port
PowerDC adapter
LED Life Time> 20,000 hours
Operating SystemMicrosoft Windows 7, 8, 10
Operating Condition0°C- 42°C, 5%-99% RH non-condensing
Warranty1 year

Field of Views

Field of View1.25x: 19x19mm

2x: 9.31x7mm

4x: 7.8×5.85mm

5x: 6.8×5.11mm

10x: 3.4×2.55mm

20x: 1.52×1.14mm

40x: 7.8×5.85mm

Microscope Models:

iS510Brightfield and Epifluor Imaging (Per specification table)

includes iS500-OEM plus focus, enclosure

no obj lens, no XY stage

iS500BFiS500 with Brightfield imaging Only
iS510-OEMBrightfield and Epifluor Imaging

includes just the epi-fluorescnce module (filter cube, filters), BF and FL LEDs, camera, PCB and software

iS510TiS500 with Tablet PC or Retina Display
iS520iS500 with BF and 2 Fl channels
iS530iS500 with BF and 3 FL channels

IncuScope Accessories

  • Customized any fluorescence filters from UV to Infrared
  • Various Camera Selections, i.e. different resolution (1.4MP to 16MP), speed (1-90 fps) and chip size (1/3”-1”).
  • Objective lenses: 1.25x, 2x, 4x, 5x, 0x, 20x, 40x, 50x (oil), 60x (dry), 100x (water, or air/oil)

1. LED Selection

You select the LEDs, we will select the proper excitation emission and barrier filters.



Minimum LED

Power Output

Applications/ Fluorophores
Deep UV265 nm10 mW
Deep UV280 nm25 mW
Deep UV300 nm40 mW
Deep UV340 nm53 mW
UV365 nm190 mW
UV365 nm1150 mW
UV375 nm387 mWDapi/Hoecst
UV385 nm270 mW
UV385 nm1650 mW
UV395 nm400 mW
UV405 nm870 mW
UV405 nm1500 mW
Violet420 nm750 mW
Royal Blue450 nm1850 mW
Royal Blue455 nm900 mW
Blue470 nm650 mWGFP
Blue490 nm255 mW
Cyan505 nm400 mW
Green530 nm350 mW
Lime565 nm880 mW
Amber590 nm160 mWRFP/ Texas Red
Amber595 nm445 mW
Orange617 nm600 mW
Red625 nm700 mW
Deep Red660 nm940 mW
Far Red730 nm515 mW
IR780 nm200 mW
IR780 nm800 mW
IR810 nm325 mW
IR850 nm900 mW
IR850 nm1400 mW
IR880 nm300 mW
IR940 nm800 mW
IR970 nm35 mW
IR1050 nm50 mW
IR1200 nm30 mW
IR1300 nm25 mW
IR1450 nm31 mW
IR1550 nm31 mW
Broadband470 – 850 nmf70 mW
Warm White3000 Kg570 mWBrightfield
Warm White3000 Kg2000 mW
Cold White6500 Kg800 mW
Cold White6500 Kg2350 mW

2. Cameras

Order CodeSensor & Size (mm)Pixel (μm)G Sensitivity

Dark Signal

BIC-T3C-12C12MP / IMX226(C)

1/1.7″ (7.40×5.55)

1.85×1.85280mv with 1/30s

0.1mv with 1/30s

Q3/coming soon1×1,2×20.1ms~2000ms
BIC-T3C-6C6.3MP / IMX178(C)

1/1.8″ (7.37×4.92)

2.4×2.4425mv with 1/30s

0.15mv with 1/30s

[email protected]×2048

[email protected]×1024



2.5×2.5600mv with 1/30s

0.15mv with 1/30s

[email protected]×1536

[email protected]×768



2.3M / IMX185(C)


3.75×3.751120mv with 1/30s
 0.5mv with 1/30s[email protected]×12001×1,2×20.244ms~2000ms
BRC-160016MP / MN3412 (Color)


1.335 x 1.3351200mV4fps @4608×3456

16 @ 2304 x1728


We also offer CCD and sCMOS cameras, either USB 3.0 or USB2.0. Please contact us for further assistance.

3. Obj lenses


a) plan achromat

b) plan semi-apo

c) Plan apo

Magnifications: 1.25x, 2x, 4x, 5x, 10x, 20x, 40x, 50x, 60x and 100x (oil, dry or water)

4. Accessories

Mechanical stage can be installed from both right and left sides easily, even from the front.The mechanical XY stage grabs a micro-well plate directly without having any holder)
all customized shape of sample holdersT-25 Flask holder T-75 Flask holder are also available.
dimensions for the Terasaki holder. 35-mm petri-dish holders needs this adapter.

incuView Software Interface


Time-lapse mode

Controls each LED separtely

Turn ON/OFF option for teh LEDs, i.e. digital shutter

Live view and image capture

label image color

Merge images

Color and monochrome images

Manual and automatic exposure time and gain

Captures BF and FL images separately

Zoom in / Zoom out with a touch of mouse wheel

Full screen of the live image, resizable tabs

1.25x Obj Lens2x Obj Lens

40x with 16MP camera

50x obj lens with 2.3MP camera

100x (Water)

Colorful brigtfield images (available with iS500BF model only)


BIM5-4x 4X Plan Achromat, Cartilage, 16MP Camera

4x Plan Semi Apo, Cartilage, 16MP Camera

BUM5-10x 10x Plan Semi Apo, Cartilage, 16MP Camera

""20x Plan Apo, Cartilage, 16MP Camera

BIM5-40x 40x Plan Obj lens, Cartilage, 16MP Camera


50x Plan Semi Apo Obj lens, Cartilage, 16MP Camera

Following images were collected using 3 LEDs of UV, Blue and Green excitations, 3MP sCMOS camera BIC-C30, and the below-mentioned objective lenses. merged images were generated using IncuView software.

FluoCells® Prepared Slide #2: bovine pulmonary artery endothelial cells (BPAE) cells with Mouse Anti-α-tubulin, BODIPY FL Goat Anti-Mouse IgG, Texas Red-X Phalloidin, and DAPI), (Molecular Probes)

BIHR-20xBF PlanFluor EPI20XBF Plan Semi Apochromat 20X/NA0.45/WD3 Lens:

BIMJ969-60x: 60x /NA0.80/WD0.23 Plan Objective Lens:

FluoCells® Prepared Slide #6 (Muntjac cells with Mouse Anti-OxPhos Complex V Inhibitor Protein, Alexa Fluor 555 Goat Anti-Mouse IgG, Alexa Fluor 488 Phalloidin, and TO-PRO-3) (Molecular Probes)

BIMJ969-60x: 60x /NA0.80/WD0.23 Plan Objective Lens:

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